Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire

Biotechnology Skill Enhancement Program-BiSEP


(Offered by P.G Department of Biotechnology)


An initiative by the Department of Information Technology, Bio Technology and the Department of Science and Technology [IT, BT & S & T], Government of Karnataka & supported by  the Department of Bio Technology [DBT], Government of India in collaboration with the Life Sciences Sector Skill Development Council [LSSSDC], Council of Scientific and Industrial Research  -  Indian Institute of Chemical Technology [CSIR-IICT] and the Association of Bio Technology Led Enterprise [ABLE].

Post Graduate Diploma Course


  • Impart industry oriented skill upgrading training
  • Enhance employability in Biotech sector
  • Train & mentor students/faculty from different districts of Karnataka
  • Nurture the local talent and create an ecosystem of entrepreneurship and growth of Biotech sector
  • Create research environment that foster excellent R & D to address challenges in the areas of Agriculture, Health, Food & Nutrition.

Strength of P G Department of Biotechnology

  • The Department has Memorandum of Understanding (MoU) with some of the renowned companies like Aristogene, Bengaluru, Bhat Laboratories, Bengaluru, Labland Biotech Pvt Ltd, Mysore, Vidyarathana Pvt Ltd, Kerala.
  • Its alumni are presently working in Biocon , Syngene ,Metahelix , IIHR, Mylan Lab, Bengaluru.
  • Updated skill training is provided in Upstream Fermentation - Small & pilot, downstream process - Product purification, HPLC, cell culture assay, to meet the industrial demand.

Remarkable features of the  Programme

  • Unique programme with enhanced placement opportunity in Biotechnology sector
  • Emphasises on application of biological and engineering principles involving microbial, plant and mammalian systems
  • Curriculum with skilled policies accord with the industrial demand
  • Course completion merits the candidates with placements as Process Developer, Executive - upstream/downstream production, Scientist - Protein Biologist, product biology executive, Quality Control  Scientist - cultures, Manager - Q A and Q C

About Domain : Fermentation and Bioprocess

  • Rapid increase in fermentation market in Karnataka due to great demand for Fermentation Chemicals in pharmaceuticals, cosmetics, food & beverage industries.
  • High industrialisation rate in emerging economies such as China, India, South Korea, Mexico etc is anticipated to be responsible for huge market growth.
  • Potentiality of fermentation industry lies within Inter relationship among technology, market developments, strategies of producers and particularly in the supply of raw material.

The curriculum deals with the production of therapeutic proteins on using different expression systems as well as high cell density fermentation including media selection, preparation and sterilisation, fermentor functional design, sterilisation in place, sterilisation process validation, fermentor inoculation and maintenance of different fermentation parameters, scale up of fermentation process, fermentor harvest and cleaning process validation.

For animal cell culture, media preparation and sterilisation by filtration, sub-culturing, suspension culture and monitoring, monitoring of bioreactor cultures are taught.

In downstream processing, familiarisation with chromatography equipment, column packing methods, column equilibration, and operation of tangential flow filtration as well as its cleaning and sanitation, dead end filtration will also be part of the curriculum. In addition, regulatory requirements of different countries and cGMP requirements for the production area of biopharmaceuticals will also be covered.

Future prospects

  • Global fermentation market is projected to reach USD 78.38  billion billion by 2023 with growth rate of 3.46%
  • Annual consumption of fermented product is increasing at high rate of 5.83% across world. America holds major market share followed by Asia Pacific  in  year 2017. 
  • Biopharma industries include Biocon, Serum Institute of India, Panacea Biotech, Reliance Life Sciences, Shantha Biotechniques, Indian Immunologicals, Bharat Biotech, Cadila Health Care, Intervet India, Intas Biopharma, Eli Lilly, Hafkine Biopharma, Glaxo Smith Kline, Novo Nordisk, etc.

Course Details

    Domain        :  Fermentation and Bioprocess
    Duration      :  1 Year Program: Course Work - 6 month & Industry Internship - 6 month

    Fellowship   :  Rs 10,000/month (exclusive for Karnataka students)


    Masters’ Degree(Life Sciences - Biotechnology / Microbiology / Biochemistry/Bioinformatics or any other Life sciences related courses) or  B E/B Tech (Biotechnology/Bioinformatics) or Bachelor of Pharmacy / Agriculture/Veterinary or any 4 years degree courses in Life Science subjects. The minimum marks for students belonging to SC/ST categories shall be not less than 40% and for all other categories it shall be not be less than 50% in the qualifying degree examination.


    Rs.50,000/- per student excluding(hostel & examination fees ), for non Karnataka student. The resident students of Karnataka joining the course under BiSEP to pay Rs.25,000/-only as course fee. Successful applicants will be benefited with a fellowship of Rs 10,000/-pm from KBITS


Admission Procedure

    Admission shall be done through online entrance test “Karnataka – Biotechnology Aptitude Test (K-BAT). Ranking is generated for each candidate with the weightage of 50% marks of the Entrance Test and 50 % marks of the Qualifying Examination. The candidates securing upto 50% marks belonging to general category/OBCs and 40% for candidates belonging to SC/ST category will be called for Counselling and Seat Allotment to select their choice of domain and institute based on the availability of domain and institute.

    Seat Matrix in each Institute

    Total 20 seats in each institute; 10 seats are reserved for Resident Students of Karnataka & 10 seats for Non-resident Students of Karnataka. Reservations for students belonging to OBCs/SC/ST and Hyderabad - Karnataka regions are provided as per Government norms.


    Seat Reservation / Category







    Resident Students of Karnataka







    Non-Resident Students of Karnataka category







    *OBC reservation under non-resident students of Karnataka category, wherever applicable will be implemented as per the policy of each participating University/Institute.


    Co ordinator BiSEP Course

    P.G Department of Biotechnology

    Sri Dharmasthala Manjunatheshwara College (Autonomous), Ujire-574 240 +91-9844186023 +91-9448943404


    Admission through Biotechnology Aptitude Test (KBAT)

    For more details contact URL :